Toxic Indian cough syrup turns up in Micronesia

Contaminated cough syrup made by an Indian company has been found in the Marshall Islands and Micronesia, the World Health Organisation (WHO) said on Tuesday, after a spate of child deaths linked to other syrups in some countries last year.

The WHO statement did not say whether any children in the Marshall Islands or Micronesia had fallen sick. But it said samples from a batch of imported cough syrup, with the product name Guaifenesin Syrup TG Syrup, were contaminated with unacceptable amounts of diethylene glycol and ethylene glycol, which are toxic to humans when consumed and can prove fatal.

The contamination was identified by Australia's regulator, the Therapeutic Goods Administration (TGA).

The new alert comes after three similar warnings issued last year by the WHO about contaminated cough syrups for children. These syrups, made by different manufacturers in India and Indonesia, have been linked to the deaths of more than 300 children — most of them aged under 5 — from acute kidney injury in Gambia, Indonesia and Uzbekistan.

The stated manufacturer of the medicines in the latest alert was India’s QP Pharmachem, based in Punjab state and the marketer of the product was Trillium Pharma, based in Haryana state, the WHO said.

Neither QP Pharmachem nor Trillium have provided guarantees to WHO on the safety and quality of these products, the agency said in the statement.

QP Pharmachem MD Sudhir Pathak said it had tested a sample from the exported batch after a recent query from the local state drug regulator.

“We found it satisfactory and the regulator found it satisfactory too,” he said.

Pathak said the product also is distributed in India and the company has not received any complaints so far.

Pathak said QP Pharmachem had permission from the Indian government to export 18,000 bottles of the syrup only to Cambodia. It was unclear how the product ended up in the Marshall Islands and Micronesia.

Trillium Pharma did not immediately respond to a request for comment.

The WHO said countries needed to step up surveillance to find more contaminated products. Its head of substandard medicines, Rutendo Kuwana, said earlier this month that it was working with countries to test medicines when asked to do so, after issuing a global call to action in January to help prevent more deaths.

“We are trying to collect samples and test them,” he said. 

Reuters