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New York — Decaffeinated coffee and reduced-sugar soft drinks have had their day. Now, according to a small biotechnology company, it’s time for low-nicotine cigarettes.

Altria Group and RJ Reynolds Tobacco told regulators two years ago that such a product might not be possible. On Friday, their claims may be up-ended as 22nd Century Group, a New York-based company, goes before the Food and Drug Administration (FDA) seeking to market cigarettes with 95% less nicotine than conventional ones...

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