A senior scientist from the biggest external funder of SA HIV research says he remains optimistic about the prospects of an effective vaccine, despite the failure of the HVTN 702 trial.

The experimental HVTN 702/Uhambo trial, funded by the US National Institutes of Health (NIH) and the Bill & Melinda Gates Foundation, tested a modified version of the 2009 Thai RV144 vaccine, the only one to date to provide some protection against the virus. But the trial, which was conducted among 5,400 volunteers at 14 different sites in SA, was halted early because it did not work. ..

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