It should be a moment of cautious optimism: a second promising vaccine has become available to tackle the Ebola outbreak in the Democratic Republic of Congo (DRC). Instead, there is uncertainty and angst.

Clinicians desperately want to see the new vaccine deployed. But officials in the DRC, unnerved by public reaction to an earlier experimental vaccine, worry that introducing a second one might stoke public suspicions and destabilise containment efforts. Experts met in the capital, Kinshasa last week to work out which way to jump.

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