Disruption is the playground of most entrepreneurs. Like an earthquake that breaks apart proud structures that have stood for years, so disruption changes industries and shakes up dominant companies. Big-thinking entrepreneurs thrive amid this destruction. They are found in its wake, occupying the cracks and the fault lines, rebuilding, making what was once there better and sometimes bigger. It's a small irony that it is in San Francisco, known for its earthquake risk, that the biggest entrepreneurial disruptions in history have happened. Entrepreneurs have capitalised on fault lines in many industries, from transport (Uber) to advertising (Facebook and Google), hospitality (Airbnb), finance (blockchain, robo-advice) and broadcast media (podcasting and video streaming) ... the list goes on. And the disruption proliferates, giving rise to a global entrepreneurial class that is generating a new wave of wealth and is itself shaking up traditional ways of investment and raising money. I...

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