Frankfurt — A class of treatments known as antibody-drug conjugates (ADC), which combine cancer-tracking proteins with powerful cell toxins, are getting a fresh start as dozens of drugmakers test a record number of new compounds in people.

Nearly 20 years after the first ADC, Pfizer’s Mylotarg, was approved, developers say they are now getting a handle on the technology that was long seen as an elegant concept, but one that presented many clinical challenges...

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