Tristen Sweeten, a 34-year-old nurse in Utah, hopes her three children will receive Moderna’s Covid-19 vaccine through its paediatric clinical trial. The sooner the better, she said, for their safety and the greater goal of ending the pandemic.

Angie Ankoma, a 45-year-old black mother of four who works in philanthropy in Rhode Island, believes trials must include diverse populations, and participated in one for a Covid-19 vaccine herself. Volunteering her children for possible inclusion in Moderna’s trial was a tougher call...

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