Dubai — Venezuela’s most high-profile opposition figures were seized from their homes by security forces, according to people close to them, in what appeared to be a crackdown on officials challenging the government of President Nicolas Maduro. Opposition leader Leopoldo Lopez was taken from his home at gunpoint, his wife said, just weeks after he had been transferred from a military prison to house arrest after three years behind bars. Caracas mayor Antonio Ledezma was also seized, according to his wife. Videos of the detentions were posted on Twitter. “They’ve just taken Leopoldo from the house,” Lilian Tintori, his wife, said on Twitter. “We don’t know where he is or where they are taking him.” Lopez has become a symbol for rights groups and foreign governments, who have said his detention — including stints in solitary confinement — was clear evidence that Maduro was willing to trample basic rights to safeguard his power. As Venezuelans suffer food shortages and as street violen...

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