GLAXOSMITHKLINE is pinning the future of its HIV business on an audacious bet: upending the decades-old treatment strategy that has turned a fatal illness into a chronic condition.The treatment of HIV, the virus that causes AIDS, has changed little since the mid-1990s, when the introduction of a new class of drug dramatically improved HIV therapy.Doctors found that combining the newer type of antiretroviral drug with two drugs from an earlier class hindered the virus from developing resistance. A three-drug regimen has remained the standard approach since then, with drug development efforts focused on making ever more powerful triple combinations.Glaxo executives want to change that. They hope the UK-based drug company’s latest HIV pill is powerful enough to suppress the virus with the help of just one other drug. That, according to chief executive Andrew Witty, would be a "game-changer", because taking fewer drugs would produce fewer side effects.Now, Glaxo’s majority-owned HIV bus...

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