Barcelona — Novak Djokovic suffered a surprise second-round exit at the Barcelona Open on Wednesday when the Serb was beaten 6-2 1-6 6-3 by world No140 Martin Klizan.
But favourite Rafael Nadal eased past fellow Spaniard Roberto Carballes-Baena 6-4 6-4 to reach the third round.
Second seed Grigor Dimitrov of Bulgaria also slipped past Frenchman Gilles Simon 6-2 6-1 to reach the last 16.
Djokovic, who received a bye in the opening round, has not made the last eight of a tournament since Wimbledon 2017.
Nadal will now meet Guillermo Garcia-Lopez, who progressed after 14th seed Kei Nishikori retired from his first match after experiencing pain in his right wrist.