We've got news for you.

Register on BusinessLIVE at no cost to receive newsletters, read exclusive articles & more.
Register now

New safety concerns have emerged about the HIV drug dolutegravir, which the government plans to roll out in April. In 2018 drug regulators warned of potential harm to babies born to women who took dolutegravir during early pregnancy, after preliminary findings from a small study in Botswana showed an increased risk of neural tube defect. Now there is growing evidence that dolutegravir and other integrase inhibitors are associated with significant weight gain, particularly among black women, according to research published the Journal of Virus Eradication in January. The findings have implications for both individuals and public health, given SA’s obesity epidemic: more than two thirds of women, and almost a third of men are overweight or obese, according to the 2016 Demographic and Health Survey. Dolutegravir is to replace efavirenz in a generic three-drug cocktail for eligible patients starting treatment.It is an important part of the government’s plans to expand treatment to more ...

BL Premium

This article is reserved for our subscribers.

A subscription helps you enjoy the best of our business content every day along with benefits such as articles from our international business news partners; ProfileData financial data; and digital access to the Sunday Times and Sunday Times Daily.

Already subscribed? Simply sign in below.

Questions or problems? Email helpdesk@businesslive.co.za or call 0860 52 52 00. Got a subscription voucher? Redeem it now