New York  — Purdue Pharma agreed to plead guilty to criminal charges over the handling of its addictive prescription opioid OxyContin, in a deal with US prosecutors that stopped short of criminally charging its executives or wealthy Sackler family owners.

In a far-reaching agreement unveiled on Wednesday, Purdue formally admitted to criminal conduct related to distribution of its painkillers and agreed to pay $225m to resolve US justice department investigations. Prosecutors imposed significant penalties exceeding $8bn against Purdue, though the lion's share will go largely unpaid...

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