London — The timing was precise, the choreography immaculate: with two deft manoeuvres, a new generation of the Oeri-Hoffmann family marked its growing influence over the wealthiest dynasty in Switzerland.

First, seven members of the fifth generation joined the clan’s shareholder pool late in 2019, which oversees a $25bn stake in pharmaceuticals giant Roche. Then, in March, another member of that generation, Joerg Duschmale, replaced his uncle on the drugmaker’s board...

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