Washington — Novartis’s Sandoz unit agreed to pay $195m to settle US criminal charges that it conspired with other pharmaceutical companies to fix prices of generic drugs, the most significant settlement to come from a long-running justice department investigation.

Sandoz conspired with four of its competitors between 2013 and 2015 to rig drug prices, the department said Monday. The settlement marks the largest penalty obtained by the US in a domestic cartel case, the government said. Sandoz agreed to co-operate with the antitrust division’s continuing investigation...

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